Table 1.
Early symptoms (40%) |
≥1 rhinorrhea, sore throat, fever, and cough |
Syndromes |
Meningoencephalitis (55%) |
Meningoencephalomyelitis (40%) |
Myelitis (5%) |
Meningoencephalopathic symptoms |
Delirium (60%) |
Seizures (20%) |
Psychiatric symptoms (30%, depression, anxiety, psychosis, insomnia, vivid dreams) |
Headache, neck stiffness, vomiting (60%) |
Blurred vision (30%, with optic disc edema) |
Tremor (40%) |
Myelopathic symptoms |
Numbness, paresthesias, weakness (25%, signs include brisk reflexes, extensor plantars) |
Accompaniments of meningoencephalomyelitis |
Ataxia (40%) |
Autonomic dysfunction (20%; orthostasis, GI motility disorders, erectile dysfunction, bladder dysfunction) |
Peripheral neuropathy (<5%) |
GI, gastrointestinal.