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. 2019 May 16;14(5):e0216927. doi: 10.1371/journal.pone.0216927

Fig 3. IGF-I SDS.

Fig 3

(A) and IGF-I to IGFBP-3 ratio (B) in a subgroup of patients with supra-physiological level of IGF-I. The boxes represent interquartile ranges and the whiskers represent 10th and 90th percentiles. (A) In the subgroup of patients having supra-physiological level of IGF-I, some were observed to have extremely high SD scores of IGF-I since the initiation of rhGH treatment; however, such extreme values tended to disappear as treatment progressed. (B) IGF-I to IGFBP-3 ratio stayed relatively stable since 6 months of treatment.