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. 2019 May 16;14(5):e0216927. doi: 10.1371/journal.pone.0216927

Table 1. Baseline demographic characteristics of patients.

Variable Total
(n = 2,024)
GHD
(n = 1,297)
TS
(n = 197)
SGA
(n = 206)
ISS
(n = 315)
CRF
(n = 9)
Sex:
male 1048
(51.8%)
771
(59.4%)
0
(0.0%)
104
(50.5%)
167
(53.0%)
6
(66.7%)
female 976
(48.2%)
526
(40.6%)
197
(100.0%)
102
(49.5%)
148
(47.0%)
3
(33.3%)
Age (years) 8.49
(2.01, 19.23)
8.42
(2.10, 19.23)
9.24
(2.01, 18.58)
6.66
(3.04, 14.18)
9.05
(2.38, 16.10)
8.58
(2.48, 15.88)
Pubertya
pre-pubertal 793
(82.9%)
502
(87.3%)
107
(83.0%)
77
(83.7%)
105
(66.0%)
2
(100.0%)
pubertal 164
(17.1%)
73
(12.7%)
22
(17.1%)
15
(16.3%)
54
(34.0%)
0
(0.0%)
BA (years) 6.8
(0.6, 17)
6.0
(0.6, 17)
8.5
(1.0, 14)
5.5
(1.5, 13.5)
8.4
(2.0, 15.6)
8.8
(1.5, 13.5)
BA-CA (years) -1.46
(-8.83, 4.49)
-1.71
(-8.83, 2.71)
-0.87
(-5.75, 2.53)
-1.05
(-4.67, 2.51)
-0.98
(-5.30, 4.49)
-1.69
(-4.87, 0.30)
Height SDS -2.26
(-6.97, 6.23)
-2.25
(-6.97, 6.23)
-2.58
(-6.34, -0.66)
-2.23
(-5.14, -0.18)
-2.17
(-5.31, 1.54)
-2.43
(-3.54, 0.00)
BMI SDS -0.27
(-16.88, 3.47)
-0.23
(-16.88, 2.88)
0.51
(-1.92, 3.47)
-0.81
(-5.60, 2.09)
-0.58
(-4.60, 2.69)
-0.89
(-2.89, 1.61)

a Some patients’ puberty data are missing and only available data are accounted.

Data show numbers (%) or medians (min, max).

BA bone age, BMI body mass index, CA chronological age, CRF chronic renal failure, GHD growth hormone deficiency, ISS idiopathic short stature, SDS standard deviation score, SGA small for gestational age, TS Turner syndrome.