Figure 1 |. Ythdf1^−/− mice shows effective tumor control dependent on CD8⁺ T cells.

a, WT or Ythdf1^−/− mice were injected s.c. with 10⁶ B16-OVA cells. Tumor growth were monitored. One of three representative experiments is shown. b, WT or Ythdf1^−/− mice were injected s.c. with 10⁶ MC38 cells. Tumor growth was monitored. One of three representative experiments is shown. c, Percentage of tumor-infiltrating T cells and NK cells at day 12 post tumor inoculation. d, WT or Ythdf1^−/− mice were injected s.c. with 10⁶ B16-OVA cells. 200 μg of CD8- or NK-depleting antibody were administered twice a week starting on day 0. Tumor size was monitored overtime. n, numbers of mice. Data are mean ± s.e.m. and were analyzed by two-tailed unpaired Student’s t-test.