Temporal S-glutathionylation and activation of kinases after PABA/NO treatment. HL60 cells were treated for 1 h with 30 μM PABA/NO and resuspended in complete media, and aliquots were removed hourly for 6 h. Each time point was analyzed by immunoblot (top), and the corresponding relative abundance of proteins was plotted as the ratio to actin (bottom) for S-glutathionylation; the relative abundance of two bands, 37 kDa (■) and 18 kDa (●) are plotted in arbitrary units relative to actin (A); nitration (B), and phosphorylated and unmodified kinases and actin as a loading control(C). Phosphorylated p38 (●), JNK (■), and jun (▲) are plotted in arbitrary units relative to actin.