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. Author manuscript; available in PMC: 2019 May 16.
Published in final edited form as: Methods Enzymol. 2005;401:287–307. doi: 10.1016/S0076-6879(05)01019-0

Fig. 1.

Fig. 1.

Model scheme showing a means by which oxidative stress can be transmitted through a GST “switch” connecting to kinase cascades influencing cell signaling. In the example shown, TLK199 can cause a disassociation of the GST–JNK complex, activating JNK. PKC is an example of a protein susceptible to glutathionylation.