Table 3. Baseline Global Deficit Score (GDS) and HAND Stage by HIV Subtype A vs D.

Baseline Global Deficit Score HAND stage compared between participants with (1) Gag-Env subtype A and D and (2) Gag-Env-Pol subtype A and D.

GAG-ENV ANALYSIS				GAG-ENV-POL ANALYSIS
	A (n=34)	D (n=38)	p		A (n=12)	D (n=3)	p
GDS Normal (<0.5)	26 (76%)	17 (45%)	0.008		8 (67%)	1 (33%)	0.52
GDS Abnormal (≥0.5)	8 (24%)	21 (55%)			4 (33%)	2 (67%)
Baseline HAND Stage	(n=28)	(n=35)		Baseline HAND Stage	(n=11)	(n=13)
Normal	14 (50%)	10 (29%)	0.27	Normal	5 (45%)	3 (23%)	0.4
ANI	3 (11%)	3 (9%)		ANI	1 (9%)	0 (0%)
MND	8 (29%)	18 (51%)		MND	4 (36%)	7 (54%)
HAD	3 (11%)	4 (11%)		HAD	1 (9%)	3 (23%)
Symptomatic vs. Asymptomatic HAND				Symptomatic vs. Asymptomatic HAND
Normal/ANI	17 (61%)	13 (37%)	0.06	Normal/ANI	6 (55%)	3 (23%)	0.11
MND/HAD	11 (39%)	22 (63%)		MND/HAD	5 (45%)	10 (77%)

Abbreviations: Global Deficit Score (GDS); ANI: asymptomatic neurocognitive impairment; MND: mild neurocognitive disorder; HAD: HIV-associated dementia; HAND: HIV-associated neurocognitive disorder