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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2019 Jun 1;81(2):216–223. doi: 10.1097/QAI.0000000000001992

Table 4. Associations between patient characteristics at baseline and HIV-Associated Dementia (HAD).

Univariate and multivariate logistic regression analyses of predictors of HAD among HIV+ participants at their baseline visit.

UNIVARIATE ANALYSES MULTIVARIATE ANALYSIS
OR (95% CI) p OR (95% CI) p
Age (years) 1.03 (1.00, 1.06) 0.049 1.04 (1.00, 1.07) 0.04
Female Sex 1.45 (0.84, 2.52) 0.19 1.66 (0.87, 3.17) 0.12
Education (years) 0.97 (0.90, 1.06) 0.55 --- ---
Alcohol use in the past month 0.52 (0.29, 0.92) 0.02 0.61 (0.32, 1.16) 0.13
Depression (CES-D Score ≥ 16) 3.49 (1.97, 6.18) < 0.001 2.77 (1.52, 5.06) 0.001
CD4 Count < 200 cells/μL 1.89 (1.07, 3.33) 0.03 1.29 (0.62, 2.67) 0.49
Plasma HIV viral load >100,000 copies/mL 2.32 (1.33, 4.04) 0.003 2.26 (1.16, 4.42) 0.02
CSF HIV viral load > 100,000 copies/mL* 3.23 (1.00, 10.4) 0.049 --- ---
Fasting glucose (mg/dL) 1.00 (0.98, 1.02) 0.79 --- ---
AST (units/L) 1.01 (1.00, 1.02) 0.03 1.01 (1.00, 1.02) 0.11
ALT (units/L) 1.01 (1.00, 1.03) 0.1 1.00 (0.99, 1.02) 0.59
History of syphilis (TPHA positive) 0.58 (0.22, 1.5) 0.26 --- ---
*

CSF HIV viral load not included in the multivariate analysis due to small sample size.