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. Author manuscript; available in PMC: 2020 May 15.
Published in final edited form as: Cancer Res. 2019 Mar 26;79(10):2662–2668. doi: 10.1158/0008-5472.CAN-18-2460

Figure 1: DICER1 phosphorylation is associated with lower BMI and invasion of primary endometrioid cancers.

Figure 1:

A. Representative images of endometrioid cancers stained with phospho-specific DICER1 antibodies (top panels) and a phospho ERK antibody (bottom panels). B. Higher magnification of one endometrioid cancer sample displaying nuclear phosphorylated DICER1 staining. C. Based on the number of cells that were positive for phospho-DICER1 (panel A), the tumors were divided into “low to moderate” positivity for phosphorylated DICER1 or “high” positivity for phosphorylated DICER1. Bar graphs display the distribution of tumors with low-to-medium or high phospho-DICER1 with clinicopathologic feature. BMI, body mass index; LVSI, lymphovascular space invasion; Invasion, depth of myometrial invasion. p<0.01 for BMI, p=0.03 for LVSI, and p=0.02 for depth of myometrial invasion.