Table 1.
Characteristics of the 58 thyroid cell lines highlighted in the study
| Cell Line | Original Thyroid Tumor Type | Key genetic drivers |
|---|---|---|
| 8305C | Anaplastic | BRAF p.V600E |
| 8505C | Anaplastic | BRAF p.V600E |
| ACT-1 | Anaplastic | NRAS p.Q61K |
| ASH-3 | Anaplastic | NRAS p.Q61R |
| B-CPAP | Papillary | BRAF p.V600E |
| BHT-101 | Anaplastic | BRAF p.V600E |
| C-643 | Anaplastic | HRAS p.G13R |
| CAL-62 | Anaplastic | KRAS p.G12R |
| CUTC48 | Papillary | CCDC6-RET fusion |
| CUTC5 | Papillary | BRAF p.V600E |
| CUTC6 | Adenomatoid nodule | NRAS p.Q61K |
| CUTC60 | Anaplastic | BRAF p.V600E |
| CUTC61 | Follicular | HRAS p.Q61R |
| EAM306 | Follicular | NRAS p.Q61R |
| FTC-133 | Follicular | NF1 p.C167*, PTEN p.R130*, TP53 p.R273H |
| FTC-236 | Follicular | PTEN p.R130*, TP53 p.R273H |
| FTC-238 | Follicular | PTEN p.R130*, TP53 p.R273H |
| HTC-C3 | Anaplastic | BRAF p.V600E |
| HTh104 | Anaplastic | BRAF p.V600E |
| HTh7 | Anaplastic | NRAS p.Q61R |
| HTh74 | Anaplastic | NF1 p.L732fs |
| HTh83 | Anaplastic | HRAS p.Q61R |
| IHH-4 | Anaplastic | BRAF p.V600E |
| JEM493 | Anaplastic | HRAS p.Q61R |
| K1 (GLAG-66) | Papillary | BRAF p.V600E |
| KAT-18 | Anaplastic | Unknown |
| KHM-5M | Anaplastic | BRAF p.V600E |
| KMH-2 | Anaplastic | NRAS p.Q61R |
| KTC-1 | Papillary | BRAF p.V600E |
| KTC-2 | Anaplastic | BRAF p.V600E |
| LAM1 | Papillary | BRAF p.V600E |
| LAM136 | Papillary | BRAF p.V600E |
| MDA-T120 | Papillary | BRAF p.V600E |
| MDA-T32 | Papillary | BRAF p.V600E |
| MDA-T41 | Papillary | BRAF p.V600E |
| MDA-T85 | Papillary | BRAF p.V600E |
| MZ-CRC-1 | Medullary | RET M918T |
| Nthy-ori-3-1 | Normal thyroid | N/A |
| OCUT-1 | Anaplastic | BRAF p.V600E |
| OCUT-2 | Anaplastic | BRAF p.V600E |
| SDAR1 | Follicular | PTEN V54fs, TP53 p.R282P |
| SDAR2 | Follicular | PTEN V54fs, TP53 p.V217fs |
| SW1736 | Anaplastic | BRAF p.V600E |
| T235 | Anaplastic | BRAF p.V600E |
| T238 | Anaplastic | BRAF p.V600E |
| T241 | Anaplastic | PTEN D252fs |
| T243 | Poorly-Differentiated | MSH2 p.Q130fs, microsatellite instability |
| T351 | Poorly-Differentiated | NF1 p.Q28* |
| TCO-1 | Anaplastic | BRAF p.V600E |
| THJ-16T | Anaplastic | MKRN1-BRAF fusion |
| THJ-21T | Anaplastic | BRAF p.V600E |
| THJ-29T | Anaplastic | FGFR2-OGDH fusion |
| THJ529 | Poorly-Differentiated | BRAF p.V600E |
| THJ560 | Anaplastic | BRAF p.V600E |
| TPC-1 | Papillary | CCDC6-RET fusion |
| TT | Medullary | RET C634W |
| TT2609-CO2 | Follicular | NRAS p.Q61R |
| TTA-1 | Anaplastic | Unknown |