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. Author manuscript; available in PMC: 2020 May 15.
Published in final edited form as: Cancer Res. 2019 Apr 2;79(10):2536–2548. doi: 10.1158/0008-5472.CAN-18-2170

Figure 1. Gene expression analysis.

Figure 1.

(A) Number of transcripts significantly altered in response to TMZ (100 μM, 16 hrs) in U87 cells expressing indicated shRNA (FDR<0.05). (B) List of genes most significantly altered (FDR < 0.01) following TMZ treatment in cells expressing sh-control but not sh-p50/p105. (C) RNA expression in U87 cells expressing sh-control or sh-p105 following treatment with TMZ (100 μM, 16 hrs). Data show mean expression relative to GAPDH, ±SD of triplicate samples from two biological experiments normalized to vehicle. Inset: immunoblot in U87 cells expressing control or p105 shRNA. *, p< 0.05.