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. Author manuscript; available in PMC: 2020 May 15.
Published in final edited form as: Cancer Res. 2019 Apr 2;79(10):2775–2783. doi: 10.1158/0008-5472.CAN-18-3565

Fig. 4. Dynamic CEST MRI contrast in tumors with different DCK activity.

Fig. 4

(A) Dynamic changes for the mean ΔMTRasym (2ppm) in the two tumors and muscle. Data are presented as mean±SEM of all the pixels within each ROI (n=4). (B) Overlay image showing the AUC (area under the curve) of the three regions over the period 0 to 60 minutes post-injection. (C) Comparison of the mean AUC (0–60 min) between DCK(+) tumors and DCK(−) tumors (n=4; two-tailed Student’s t-test, *: p<0.05). (D) Overlay image showing the AUC (area under the curve) of the three regions over the period 30 to 60 minutes post-injection. (E) Comparison of the mean AUC (30 −60 min) between DCK (+) tumors and DCK (−) tumors (n=4; two-tailed Student’s t-test, *:p<0.05).