Table 2.
Comparison of original vs updated KDRI coefficients
| Donor Factors | See Footnote | Updated log HR | Updated SE | Original log HR | Original SE | Signif. Different? |
|---|---|---|---|---|---|---|
| Race: African American | 0.1452 | 0.0128 | 0.179 | 0.0306 | No | |
| Age-40 | a | 0.0073 | 0.0008 | 0.0128 | 0.0011 | Yes |
| Age-20, if age <20 | b | −0.0250 | 0.0024 | −0.019 | 0.0048 | No |
| Age-40, if age >40 | c | 0.0074 | 0.0012 | 0.0107 | 0.0026 | No |
| Height – 170, age > 12, per 10cm | d | −0.0288 | 0.0060 | −0.0464 | 0.0081 | No |
| Wt – 80, per 5kg, if age >12 | e | −0.0105 | 0.0027 | −0.0199 | 0.0050 | No |
| Wt-80, per 5kg, if age>12) and Wt >80 | f | 0.0111 | 0.0039 | 0 | 0 | Yes |
| Cr-1 | 0.1267 | 0.0148 | 0.220 | 0.0333 | Yes | |
| Cr-1.5, if Cr > 1.5 | −0.1130 | 0.0211 | −0.209 | 0.0472 | No | |
| Donation after circulatory death | 0.0971 | 0.0159 | 0.133 | 0.0581 | No | |
| Cause of death: stroke | 0.0611 | 0.0100 | 0.088 | 0.0219 | No | |
| HCV positive | 0.2742 | 0.0277 | 0.240 | 0.0600 | No | |
| Diabetes history 0–5 years | g | 0.1530 | 0.0220 | 0.130 | 0.0434 | No |
| Diabetes history 6–10 years | g | 0.2875 | 0.0349 | 0.130 | 0.0434 | Yes |
| Diabetes history > 10 years | g | 0.3563 | 0.0338 | 0.130 | 0.0434 | Yes |
| Diabetes history yes, duration unknown | g | 0.2059 | 0.0441 | 0.130 | 0.0434 | No |
| Hypertension history 0–5 years | h | 0.0853 | 0.0130 | 0.1260 | 0.0245 | No |
| Hypertension history 6–10 years | h | 0.1136 | 0.0198 | 0.1260 | 0.0245 | No |
| Hypertension history > 10 years | h | 0.1344 | 0.0190 | 0.1260 | 0.0245 | No |
| Hypertension history yes, duration unknown | h | 0.0854 | 0.0213 | 0.1260 | 0.0245 | No |
| Greater than 20 pack-year | i | 0.0260 | 0.0094 | 0 | 0 | Yes |
a.
Test applies to ages 20 to 40, considering the positioning of the knots in the original (ages 18 and 50) and updated (ages 20 and 40) KDRI formulas.
b.
Coded as (age – 18)I(age <18) in the original KDRI formula.
c.
Coded as (age – 50)I(age >50) in the original KDRI formula.
d.
Height parameter applies to all ages in original KDRI formula.
e.
Weight parameter applies to all ages in original KDRI formula.
f.
No change-point at 80 kg in original KDRI formula.
g.
In original KDRI formula, donor diabetes (yes vs no) was included.
h.
In original KDRI formula, donor hypertension (yes vs no) was included.
i.
Smoking was not included in original KDRI formula.