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Effects of ischemia and DIM on HDAC activity in primary cultures of mouse hippocampal cells at 7 DIV. The cells were subjected to ischemia alone or in combination with DIM for 6 h. The results are presented as a percentage of the normoxic control values. The bars represent the mean of three independent experiments ± SEM. The number of replicates in each experiment ranged from 5 to 8. ***p < 0.001 versus normoxic control cultures, ###p < 0.001 versus ischemic control cultures
