Table 1.
Association between RUNX2 expression and clinicopathological variables of the studied CRC patients
| Variables | Low RUNX2 expression (n = 73) | High RUNX2 expression (n = 51) | P |
|---|---|---|---|
| n (%) | n (%) | ||
| Age | |||
| >65 | 16 (21.92) | 7 (13.73) | 0.3481 |
| ≤65 | 57 (78.08) | 44 (86.27) | |
| Gender | |||
| Male | 41 (56.16) | 37 (72.55) | 0.0894 |
| Female | 32 (43.84) | 14 (27.45) | |
| Tumor site | |||
| Rectum | 40 (54.79) | 33 (64.71) | 0.3543 |
| Colon | 33 (45.21) | 18 (35.29) | |
| Tumor differentiation | |||
| Well | 18 (24.66) | 21 (41.18) | 0.0761 |
| Moderate + poor | 55 (75.34) | 30 (58.82) | |
| TNM stage | |||
| Stage II | 37 (50.68) | 10 (19.61) | 0.0006 |
| Stage III | 36 (49.32) | 41 (80.39) | |
| Lymph vascular invasion | |||
| Positive | 48 (65.75) | 38 (74.51) | 0.3282 |
| Negative | 25 (34.25) | 13 (25.49) | |
| Perineural invasion | |||
| Positive | 56 (76.71) | 42 (82.35) | 0.8301 |
| Negative | 17 (23.29) | 9 (17.65) | |
| Liver metastasis | |||
| Positive | 10 (13.70) | 21 (41.18) | 0.0007 |
| Negative | 63 (86.30) | 30 (58.82) | |
| Lung metastasis | |||
| Positive | 1 (1.37) | 8 (15.69) | 0.0035 |
| Negative | 72 (98.63) | 43 (84.31) | |
The bold P values are considered statistically significant