Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 May 16;9:7501. doi: 10.1038/s41598-019-43928-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Hepatic CIDEC2 expression progressively increased with steatosis and NASH in obese patients. (A) Liver CIDEA, CIDEB and CIDEC2 mRNA expression levels were analyzed by real-time quantitative PCR in lean patients (n = 5), in morbidly obese patients without NAFLD (n = 5), with hepatic steatosis (n = 14) and with NASH (n = 9). The gene expression values were normalized to RPLP0 mRNA levels. Results are expressed relative to the expression level in controls (means ± SEM) and statistically analyzed using the Mann–Whitney test. (B, C) Correlation between hepatic CIDEC2 expression (fold) with hepatic steatosis (%), ALT, NASH and NAFLD activity score (NAS), serum markers of hepatocyte apoptosis (caspases-generated keratin 18 fragment) and hepatocyte death (keratin 18) in 25–28 obese patients were analyzed using the Pearson’s correlation test.