Table 4.
Frequency of NRTI resistance
| Type of mutation | Frequency | In ARV drug resistance (n=43) | In first-line ARV failure (n=47) |
|---|---|---|---|
| D67N* | 12 | 27.9 | 25.5 |
| V75M | 16 | 37.2 | 34.0 |
| V75IM | 1 | 2.3 | 2.1 |
| V106I | 2 | 4.7 | 4.3 |
| V108I | 5 | 11.6 | 10.6 |
| V118I | 4 | 9.3 | 8.5 |
| K65R | 5 | 11.6 | 10.6 |
| K70R* | 16 | 37.2 | 34.0 |
| K101Q | 2 | 4.7 | 4.3 |
| K101H | 2 | 4.7 | 4.3 |
| K210R | 1 | 2.3 | 2.1 |
| K219E* | 4 | 9.3 | 8.5 |
| K219E/Q* | 2 | 4.7 | 4.3 |
| K219Q* | 7 | 16.3 | 14.9 |
| T69D | 2 | 4.7 | 4.3 |
| T69N | 11 | 25.6 | 23.4 |
| T215Y | 2 | 4.7 | 4.3 |
| T215F* | 12 | 27.9 | 25.5 |
| T215FS | 1 | 2.3 | 2.1 |
| T215F/Y | 1 | 2.3 | 2.1 |
| M41L* | 6 | 14.0 | 12.8 |
| M184I/V | 2 | 4.7 | 4.3 |
| M184V | 38 | 88.4 | 80.9 |
| A62V | 2 | 4.7 | 4.3 |
| A98G | 1 | 2.3 | 2.1 |
| L74V | 3 | 7.0 | 6.4 |
| L210W* | 5 | 11.6 | 10.6 |
| F77L | 2 | 4.7 | 4.3 |
| F116Y | 2 | 4.7 | 4.3 |
| Q151M | 3 | 7.0 | 6.4 |
| E44D | 2 | 4.7 | 4.3 |
| H208Y | 1 | 2.3 | 2.1 |
Note: *TAMs.
Abbreviations: ARV, antiretroviral; NRTI, nucleoside reverse transcriptase inhibitor.