Table 3. Univariate and multivariate analysis (Cox regression model) of OS and DFS in relation to various parameters and TSLP overexpression.
| Parameter | OS | DFS | ||||
|---|---|---|---|---|---|---|
| Univariate# | Multivariate## | Univariate# | Multivariate## | |||
| P value | P value | Risk ratio (95% CI) | P value | P value | Risk ratio (95% CI) | |
| TSLP IHC | <0.001* | <0.001* | 7.308 | <0.001* | <0.001* | 7.399 |
| Low(-)/Over(+) | (3.538–15.09) | (3.507–15.61) | ||||
| Age, y | 0.001* | 0.150 | 1.428 | 0.001* | 0.115 | 1.486 |
| <60/≥60 | (0.879–2.321) | (0.908–2.432) | ||||
| FIGO stage | <0.001* | 0.834 | 1.069 | 0.000* | 0.725 | 1.117 |
| <IIIC//≥IIIC | (0.573–1.992) | (0.602–2.074) | ||||
| Histologic differentiation | 0.006* | 0.495 | 1.331 | 0.005* | 0.917 | 0.962 |
| Well/Mod and poorly | (0.585–3.027) | (0.465–1.990) | ||||
| Pelvic involvement | <0.001* | <0.001* | 3.718 | 0.000* | 0.003* | 2.731 |
| No/Yes | (1.837–7.526) | (1.396–5.343) | ||||
| Lymph node involvement | 0.010* | 0.210 | 1.416 | 0.009* | 0.202 | 1.428 |
| No/Yes | (0.822–2.438) | (0.826–2.468) | ||||
| Presence of ascites | 0.078 | 0.086 | ||||
| No/Yes | ||||||
| Menopause | 0.106 | 0.093 | ||||
| No/Yes | ||||||
TSLP IHC Low expression: total score 0–4; TSLP IHC Overexpression: total score 5–12.
OS: the time between the date of initial diagnosis and death or last contact;
DFS: the time between the date of surgery and identification of disease recurrence;
CI: confidence interval.
#
Statistical analyses were performed by log-rank test.
##
Statistical analyses were performed by Cox regression model.
*
P<0.05 was considered significant.