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. 2019 May 17;39(5):BSR20182347. doi: 10.1042/BSR20182347

Figure 3. B-cell subpopulations show a transient skewing after LPS challenge.

Figure 3

(A) Naïve B cells showed an increase in relative numbers at 3 h after LPS challenge, whereas (B) memory B cells declined. Relative numbers normalized after 24 h and did not differ from the placebo condition. (C) Plasmablasts increased 3 h after LPS application and normalized at 24 h. Absolute counts are given for the same subsets (D–F). Mean ± SEM are given for each time-point measured over 72 h under LPS- (gray) and placebo condition (black); n=20. Two-way repeated measure ANOVA analyses were performed followed by post-hoc Bonferroni-corrected paired t tests. *P<0.05, **P<0.01, ***P<0.001, results of post-hoc Bonferroni-corrected t tests. For results of ANOVA, see text. (*) P<0.05, results from post-hoc t test, remain non-significant after Bonferroni correction.