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. 2019 May 14;39(5):BSR20190027. doi: 10.1042/BSR20190027

Table 4. Diagnostic sensitivity and specificity for groups of serum proteins in NPC efficacy.

Variables in Model Sensitivity Specificity Youden index AUC Correct rate
SPARC 0.765 0.667 0.431 0.716 0.705
SERPIND1 0.765 0.630 0.394 0.697 0.681
C4B 0.706 0.667 0.372 0.686 0.681
PPIB 0.706 0.630 0.336 0.668 0.659
FAM173A 0.647 0.667 0.313 0.657 0.659
SPARC SERPIND1 0.588 0.926 0.514 0.809 0.795
SPARC FAM173A 0.765 0.667 0.431 0.804 0.727
SERPIND1 C4B 0.529 0.926 0.455 0.792 0.772
SPARC C4B 0.765 0.667 0.431 0.794 0.750
SERPIND1 PPIB 0.765 0.630 0.394 0.785 0.727
C4B FAM173A 0.412 0.963 0.374 0.777 0.750
C4B PPIB 0.787 0.588 0.588 0.769 0.841
SPARC PPIB 0.418 0.765 0.431 0.770 0.705
PPIB FAM173A 1.00 0.407 0.407 0.754 0.681
SERPIND1 FAM173A 0.765 0.630 0.394 0.761 0.704
SPARC C4B FAM173A 0.882 0.778 0.660 0.878 0.818
SERPIND1 C4B PPIB 0.765 0.815 0.579 0.862 0.795
C4B PPIB FAM173A 0.706 0.963 0.669 0.842 0.864
SPARC SERPIND1 C4B 0.941 0.741 0.682 0.883 0.818
SPARC SERPIND1 FAM173A 0.882 0.778 0.660 0.877 0.818
SERPIND1 C4B FAM173A 0.824 0.741 0.564 0.852 0.795
SPARC SERPIND1 PPIB 0.882 0.778 0.660 0.867 0.818
SPARC PPIB FAM173A 0.941 0.704 0.645 0.795 0.862
SERPIND1 PPIB FAM173A 0.941 0.704 0.645 0.795 0.855
SPARC C4B PPIB 0.647 0.889 0.535 0.815 0.795
SERPIND1 C4B PPIB FAM173A 0.706 0.963 0.669 0.914 0.863
SPARC SERPIND1 C4B FAM173A 0.824 0.963 0.786 0.928 0.909
SPARC C4B PPIB FAM173A 0.882 0.889 0.771 0.939 0.886
SPARC SERPIND1 C4B PPIB 0.941 0.852 0.793 0.886 0.902
SPARC SERPIND1 PPIB FAM173A 0.824 0.926 0.749 0.886 0.922
SPARC SERPIND1 C4B PPIB FAM173A 0.941 0.926 0.867 0.968 0.932

PPIB, peptidylprolyl isomerase B.