Table 4. Diagnostic sensitivity and specificity for groups of serum proteins in NPC efficacy.
Variables in Model | Sensitivity | Specificity | Youden index | AUC | Correct rate |
---|---|---|---|---|---|
SPARC | 0.765 | 0.667 | 0.431 | 0.716 | 0.705 |
SERPIND1 | 0.765 | 0.630 | 0.394 | 0.697 | 0.681 |
C4B | 0.706 | 0.667 | 0.372 | 0.686 | 0.681 |
PPIB | 0.706 | 0.630 | 0.336 | 0.668 | 0.659 |
FAM173A | 0.647 | 0.667 | 0.313 | 0.657 | 0.659 |
SPARC SERPIND1 | 0.588 | 0.926 | 0.514 | 0.809 | 0.795 |
SPARC FAM173A | 0.765 | 0.667 | 0.431 | 0.804 | 0.727 |
SERPIND1 C4B | 0.529 | 0.926 | 0.455 | 0.792 | 0.772 |
SPARC C4B | 0.765 | 0.667 | 0.431 | 0.794 | 0.750 |
SERPIND1 PPIB | 0.765 | 0.630 | 0.394 | 0.785 | 0.727 |
C4B FAM173A | 0.412 | 0.963 | 0.374 | 0.777 | 0.750 |
C4B PPIB | 0.787 | 0.588 | 0.588 | 0.769 | 0.841 |
SPARC PPIB | 0.418 | 0.765 | 0.431 | 0.770 | 0.705 |
PPIB FAM173A | 1.00 | 0.407 | 0.407 | 0.754 | 0.681 |
SERPIND1 FAM173A | 0.765 | 0.630 | 0.394 | 0.761 | 0.704 |
SPARC C4B FAM173A | 0.882 | 0.778 | 0.660 | 0.878 | 0.818 |
SERPIND1 C4B PPIB | 0.765 | 0.815 | 0.579 | 0.862 | 0.795 |
C4B PPIB FAM173A | 0.706 | 0.963 | 0.669 | 0.842 | 0.864 |
SPARC SERPIND1 C4B | 0.941 | 0.741 | 0.682 | 0.883 | 0.818 |
SPARC SERPIND1 FAM173A | 0.882 | 0.778 | 0.660 | 0.877 | 0.818 |
SERPIND1 C4B FAM173A | 0.824 | 0.741 | 0.564 | 0.852 | 0.795 |
SPARC SERPIND1 PPIB | 0.882 | 0.778 | 0.660 | 0.867 | 0.818 |
SPARC PPIB FAM173A | 0.941 | 0.704 | 0.645 | 0.795 | 0.862 |
SERPIND1 PPIB FAM173A | 0.941 | 0.704 | 0.645 | 0.795 | 0.855 |
SPARC C4B PPIB | 0.647 | 0.889 | 0.535 | 0.815 | 0.795 |
SERPIND1 C4B PPIB FAM173A | 0.706 | 0.963 | 0.669 | 0.914 | 0.863 |
SPARC SERPIND1 C4B FAM173A | 0.824 | 0.963 | 0.786 | 0.928 | 0.909 |
SPARC C4B PPIB FAM173A | 0.882 | 0.889 | 0.771 | 0.939 | 0.886 |
SPARC SERPIND1 C4B PPIB | 0.941 | 0.852 | 0.793 | 0.886 | 0.902 |
SPARC SERPIND1 PPIB FAM173A | 0.824 | 0.926 | 0.749 | 0.886 | 0.922 |
SPARC SERPIND1 C4B PPIB FAM173A | 0.941 | 0.926 | 0.867 | 0.968 | 0.932 |
PPIB, peptidylprolyl isomerase B.