Figure 7. Si-Notch reduced the effect of microRNA-208a on oxidative stress and inflammation in vitro model.
Notch and p65 protein expression (A,B) by Western blotting; Notch and p65 protein expression (C) by statistical analysis; TNF-α (D), IL-1β (E), IL-6 (F), IL-18 (G), MDA (H), SOD (I), GSH (J), GSH-px (K) levels, and ROS levels (L). **P<0.01 versus negative control group; ##P<0.01 versus down-regulation of microRNA-208a group.
Abbreviations: anti-208a, down-regulation of microRNA-208a group; Negative, negative control group; Si- Notch, Si- Notch and down-regulation of microRNA-208a group.