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. 2019 Apr 5;19(6):4663–4672. doi: 10.3892/mmr.2019.10137

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Copyright: © Cui et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Expression of lncRNA 430945 and ROR2 are high in human AS tissues. (A) Hematoxylin and eosin-stained representative sections of aortas from human AS tissues and Con tissues. Scale bar=50 µm. Subset of the differentially expressed (B) lncRNAs and (C) mRNAs detected in the AS tissues (n=3) and Con tissues (n=3) using microarray analysis. (D) Six lncRNAs with differential expression in AS tissues and Con tissues were validated by qPCR. (E) Expression levels of ROR2 in AS tissues and Con tissues were analyzed using qPCR. *P<0.05, vs. Con (n=3). (F) Levels of ROR2 in AS tissues and Con tissues were analyzed using western blotting. The band intensities relative to β-actin are presented as the mean ± standard deviation; n=3; *P<0.05, vs. Con. ROR2, receptor tyrosine kinase-like orphan receptor 2; lncRNAs, long non-coding RNAs; qPCR, quantitative-polymerase chain reaction; AS, atherosclerosis; Con, control (normal aortic tissues).