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. 2019 Apr 15;19(6):4553–4560. doi: 10.3892/mmr.2019.10167

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Ala treatment decreases BP and LV mass in a SHR model. SHRs were treated daily with Ala, Hyd or saline for 6 weeks, and tail arterial BP was measured weekly. (A-C) Measurements of SBP, DBP and MAP; n=6 per group. *P<0.05 vs. SHR-Ala, ^#P<0.05 vs. SHR-Hyd. (D) LV mass was measured by echocardiography; the ratio of LV mass to BW was compared among the three groups. **P<0.01. Data are presented as the mean ± standard error of the mean. Ala, alamandine; BW, body weight; DBP, diastolic blood pressure; Hyd, hydralazine; LV, left ventricle; MAP, mean arterial blood pressure; ns, no significance; SHR, spontaneous hypertensive rat; SBP, systolic blood pressure.