Table IV.
Function enrichment for genes in modules.
| Category | Term | P-value | Genes | |
|---|---|---|---|---|
| 1 | KEGG_PATHWAY | hsa00970:Aminoacyl-tRNA biosynthesis | 8.99E-05 | YARS, AARS, QARS |
| GOTERM_BP_DIRECT | GO:0006418~tRNA aminoacylation for protein translation | 3.31E-05 | YARS, AARS, QARS | |
| GOTERM_BP_DIRECT | GO:0006457~protein folding | 6.76E-04 | CCT7, AARS, CCT3 | |
| GOTERM_BP_DIRECT | GO:1904871~positive regulation of protein localization to Cajal body | 1.90E-03 | CCT7, CCT3 | |
| GOTERM_BP_DIRECT | GO:1904874~positive regulation of telomerase RNA localization to Cajal body | 3.57E-03 | CCT7, CCT3 | |
| GOTERM_BP_DIRECT | GO:0032212~positive regulation of telomere maintenance via telomerase | 7.60E-03 | CCT7, CCT3 | |
| GOTERM_BP_DIRECT | GO:0007339~binding of sperm to zona pellucida | 8.31E-03 | CCT7, CCT3 | |
| GOTERM_BP_DIRECT | GO:1901998~toxin transport | 8.55E-03 | CCT7, CCT3 | |
| GOTERM_BP_DIRECT | GO:0050821~protein stabilization | 3.20E-02 | CCT7, CCT3 | |
| 2 | KEGG_PATHWAY | hsa04650:Natural killer cell mediated cytotoxicity | 4.23E-03 | TNFSF10, CD247, KLRD1, HCST |
| KEGG_PATHWAY | hsa03013:RNA transport | 1.10E-02 | NUP214, NUP62, EIF4A1, GEMIN4 | |
| GOTERM_BP_DIRECT | GO:0007166~cell surface receptor signaling pathway | 3.33E-04 | TNFSF10, NUP62, CD247, BIRC2, KLRD1 | |
| GOTERM_BP_DIRECT | GO:0016032~viral process | 4.64E-04 | NUP214, NUP62, HDAC1, CD247, EIF4A1 | |
| GOTERM_BP_DIRECT | GO:0043066~negative regulation of apoptotic process | 2.21E-03 | MCL1, NUP62, HDAC1, BCL2A1, BIRC2 | |
| GOTERM_BP_DIRECT | GO:0043123~positive regulation of I-kappaB kinase/NF-kappaB signaling | 1.70E-02 | TNFSF10, NUP62, BIRC2 | |
| GOTERM_BP_DIRECT | GO:0050776~regulation of immune response | 2.06E-02 | CD247, KLRD1, HCST | |
| GOTERM_BP_DIRECT | GO:0043044~ATP-dependent chromatin remodeling | 2.84E-02 | HDAC1, SMARCA5 | |
| GOTERM_BP_DIRECT | GO:0006364~rRNA processing | 2.90E-02 | EXOSC10, NOP56, GEMIN4 | |
| GOTERM_BP_DIRECT | GO:0006409~tRNA export from nucleus | 3.93E-02 | NUP214, NUP62 | |
| GOTERM_BP_DIRECT | GO:0010827~regulation of glucose transport | 4.05E-02 | NUP214, NUP62 | |
| GOTERM_BP_DIRECT | GO:0097192~extrinsic apoptotic signaling pathway in absence of ligand | 4.17E-02 | MCL1, BCL2A1 | |
| 3 | KEGG_PATHWAY | hsa01100:Metabolic pathways | 1.94E-02 | ATIC, EPRS, ATP5A1, MDH2 |
| GOTERM_BP_DIRECT | GO:0006888~ER to Golgi vesicle-mediated transport | 1.32E-03 | TGFA, SERPINA1, PROS1 | |
| GOTERM_BP_DIRECT | GO:0048566~embryonic digestive tract development | 5.70E-03 | TNF, ADA | |
| GOTERM_BP_DIRECT | GO:0048208~COPII vesicle coating | 2.16E-02 | TGFA, SERPINA1 | |
| 4 | GOTERM_BP_DIRECT | GO:0002576~platelet degranulation | 3.62E-02 | SERPINA1, PROS1 |
| GOTERM_BP_DIRECT | GO:0000187~activation of MAPK activity | 3.76E-02 | TNF, TGFA | |
| GOTERM_BP_DIRECT | GO:0010951~negative regulation of endopeptidase activity | 4.25E-02 | SERPINA1, PROS1 |
KEGG, Kyoto encyclopedia of Genes and Genomes; GO, Gene Ontology; BP, biological process.