Figure 2.

TSA promotes the apoptosis of keloid fibroblasts in a time-dependent manner. (A) Annexin V and PI staining was performed to test for cell apoptosis ratios in response to 1,000 nM TSA treatment at 24, 48 or 72 h in culture. (B) Data are displayed as bar graphs. Results are presented as the mean ± standard deviation of three independent experiments (n=8). A two-tailed Student's t-test was used to compare the groups. **P<0.01 and ***P<0.001 vs. respective control. TSA, trichostatin A; PI, propidium iodide.