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. 2019 Apr 24;19(6):5251–5262. doi: 10.3892/mmr.2019.10185

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Copyright: © Jian et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Hierarchically clustered (average linkage) heatmap of TSA induction of modification in miRNA expression in keloid fibroblasts. A total of 10 miRNAs were downregulated and 22 miRNAs upregulated as demonstrated by the heatmap. Red, significantly increased expression; green, significantly decreased expression. U6 small nuclear RNA was selected as a control. n=3 for C and T groups. miRNA/miR, microRNA; TSA, trichostatin A; C, control; T, TSA-treated.