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. 2019 Apr 12;19(6):4897–4905. doi: 10.3892/mmr.2019.10158

Figure 4.

Figure 4.

Electrophysiology of endophilin 1 knockdown neurons processed by oligomeric Aβ. (A) Image of a neuron obtained from patch recording. Scale bar, 50 µm. Mean values of (B) capacitance and (C) resting membrane potentials of patched neurons in NC + Aβ and Endo1 siRNA + Aβ groups. n=10 cells per group. (D) mEPSC tracings from NC + Aβ and Endo1 siRNA + Aβ groups. (E) mEPSC frequency and (F) amplitude in NC + Aβ and Endo1 siRNA + Aβ group, n=16 cells per group, *P<0.05, **P<0.01 vs. NC + Aβ. NC, negative control; Aβ, amyloid β; Endo1, endophilin 1; siRNA, small interfering RNA; mEPSC, miniature excitatory postsynaptic current.