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. 2019 May 10;34(1):1030–1040. doi: 10.1080/14756366.2019.1609469

Table 2.

IC50 of compounds 10, 11, 13, 14, and 18 against EGFR and HER2 enzymes.

Compound no. EGFR IC50 (µM)* HER2 IC50 (µM)*
10 3.90 ± 0.03 5.40 ± 0.12
11 2.55 ± 0.17 31.31 ± 0.31
13 10.20 ± 0.10 13.01 ± 0.09
14 4.11 ± 0.02 26.03 ± 0.22
18 9.66 ± 0.08 3.20 ± 0.04
Erlotinib 6.21 ± 0.31 9.42 ± 0.21

*The values represent the mean ± SE of three independent experiments.