Table 8.

Docking results of compound 10 inside 1M17 and 3RCD active sites.

Receptor	Compound	Energy score (S) (Kcal/mol)	Amino acids	Interacting groups	Length (Å)
1M17	Erlotinib	−9.82	Met 769	N-1 of quinazolinone	2.70
	10	−9.88	Met 769	NH2 of sulphonamide	0.85
			Cys 773	CO of quinazolinone	1.91
			Phe 699	Ph of acetamide	4.23
3RCD	TAK-285	−9.70	Met 801	N-1 of pyrrolopyrimidine	2.18
	10	−9.71	Met 801	SO2 of sulphonamide	3.15
			Thr 862	CO of acetamide	1.97
			Asp 863	CO of acetamide	2.73
			Lys 753	N-1 of quinazolinone	1.87