Table 1.
Clinical characteristics
| Period 1 (n = 633) | Period 2 (n = 568) | P‐value | |
|---|---|---|---|
| Age, mean (SD), years | 63.33 (13.39) | 63.04 (13.17) | 0.71 |
| Male sex, n (%) | 280 (44.23) | 277 (48.77) | 0.12 |
| BMI, kg/m2, mean (SD) | 25.19 (3.71) | 25.12 (3.46) | 0.74 |
| Medical history, n (%) | |||
| MI | 112 (17.69) | 110 (19.37) | 0.46 |
| Prior catheterization with stenosis ≥50% | 146 (23.06) | 150 (26.41) | 0.18 |
| PCI | 116 (18.33) | 115 (20.25) | 0.40 |
| CABG | 8 (1.26) | 15 (2.64) | 0.08 |
| Heart failure | 10 (1.58) | 12 (2.11) | 0.49 |
| Hypertension | 363 (57.35) | 331 (58.27) | 0.74 |
| Diabetes mellitus | 143 (22.59) | 125 (22.01) | 0.81 |
| Dyslipidemia | 69 (10.90) | 55 (9.68) | 0.49 |
| Stroke | 82 (12.95) | 70 (12.32) | 0.74 |
| chronic kidney disease | 11 (1.74) | 7 (1.23) | 0.47 |
| Peripheral artery disease | 2 (0.32) | 1 (0.18) | 1.00 |
| Smoker (current and past) | 180 (28.44) | 156 (27.46) | 0.71 |
| Family history, n (%) | 134 (21.17) | 96 (16.90) | 0.06 |
| ECG results, n (%)a | 0.43 | ||
| Ischemic | 263 (43.33) | 259 (47.87) | |
| Non‐diagnostic ST‐T changes | 36 (5.93) | 28 (5.18) | |
| Normal | 225 (37.07) | 180 (33.27) | |
| Other | 83 (13.67) | 74 (13.68) | |
| Clinical findings, mean (SD) | |||
| Heart rateb (beats per min) | 80.07 (15.55) | 79.28 (14.73) | 0.37 |
| Systolic blood pressurec (mm Hg) | 153.08 (24.90) | 153.12 (24.42) | 0.97 |
| Diastolic blood pressurec (mm Hg) | 84.04 (14.73) | 84.47 (15.90) | 0.63 |
| First cTnI > MI cut‐off, n (%) | 69 (10.90) | 110 (19.37) | <0.01 |
| Serial cTnI in the ED, n (%) | 95 (15.01) | 61 (10.74) | 0.03 |
| Time interval to the second cTnI measurement, median (IQR), hour | 5.90 (4.27, 8.60) | 5.50 (3.97, 9.12) | 0.46 |
Abbreviations: BMI, body mass index; CABG, coronary artery bypass grafting; cTnI, cardiac troponin I; ECG, electrocardiography; ED, emergency department; IQR, interquartile range; MI, myocardial infarction; PCI, percutaneous coronary intervention.
a
Available data: n = 1138; period 1, n = 607; period 2, n = 531.
b
Available data: n = 1197; period 1, n = 632; period 2, n = 565.
c
Available data: n = 1191; period 1, n = 631; period 2, n = 560.