Table 4.
Antimicrobial susceptibility and resistance of anaerobic organisms other than B. fragilis to selected antimicrobials from 2010 to 2012.
| Percent susceptible (%S) and percent resistant (%R)b | A/Sa |
P/T |
FOX |
ETP |
IPM |
MEM |
PEN/AMP |
CC |
MXF |
MTZ |
||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N |
%S |
%R |
N |
%S |
%R |
N |
%S |
%R |
N |
%S |
%R |
N |
%S |
%R |
N |
%S |
%R |
N |
%S |
%R |
N |
%S |
%R |
N |
%S |
%R |
N |
%S |
%R |
|
| Breakpoints in μg/mL | – | ≤8/4 | ≥32/16 | – | ≤32/4 | ≥128/4 | – | ≤16 | ≥64 | – | ≤4 | ≥16 | – | – | – | – | <4 | >16 | – | – | – | – | ≤2 | ≥8 | – | ≤2 | ≥8 | – | ≤8 | ≥32 |
| Prevotella spp. | 229 | 99 | 0 | 800 | 100 | 0 | 806 | 97 | 1 | 196 | 100 | 0 | – | – | – | 234 | 100 | 0 | – | – | – | 800 | 72 | 26 | 196 | 73 | 24 | 571 | 97 | 0 |
| Fusobacterium nucleatum-necrophorum | 27 | 100 | 0 | 27 | 100 | 0 | 27 | 100 | 0 | 15 | 100 | 0 | – | – | – | 27 | 100 | 0 | – | – | – | 27 | 100 | 0 | 15 | 100 | 0 | 27 | 100 | 0 |
| Anaerobic gram-positive cocci | 150 | 88c | 9 | 614 | 99 | 0 | 148 | 94 | 3 | 150 | 83 | 9 | – | – | – | 614 | 98 | 1 | – | – | – | 614 | 79 | 16 | 150 | 63 | 20 | 611 | 96 | 3 |
| Veillonella spp. | 31 | 90 | 6 | 32 | 84 | 16 | 32 | 97 | 0 | 26 | 85 | 8 | – | – | – | 32 | 97 | 0 | – | – | – | 32 | 66 | 34 | 26 | 81 | 12 | 32 | 97 | 0 |
| Propionibacterium acnes | 58 | 100 | 0 | 58 | 100 | 0 | 58 | 100 | 0 | 58 | 100 | 0 | – | – | – | 58 | 100 | 0 | – | – | – | 58 | 91 | 9 | 58 | 93 | 3 | 58 | 9 | 91 |
| Clostridium perfringens | 108 | 100 | 0 | 348 | 100 | 0 | 108 | 99 | 0 | 69 | 100 | 0 | – | – | – | 348 | 100 | 0 | – | – | – | 348 | 86 | 7 | 69 | 100 | 0 | 348 | 100 | 0 |
| Other Clostridium spp.d | 71 | 100 | 0 | 266 | 98 | 2 | 77 | 70 | 17 | 39 | 100 | 0 | – | – | – | 266 | 99 | 0 | – | – | – | 266 | 66 | 21 | 45 | 74 | 20 | 266 | 98 | 1 |
a
The following antimicrobials were used: Ampicillin-sulbactam (A/S), Piperacillin-Tazobactam (P/T), Cefoxitin (FOX). Ertapenem (ETP), Imipenem (IPM), Meropenem (MEM). Penicillin/Ampicillin (PEN/AMP), Clindamycin (CC), Moxifloxacin (MXF), Metronidazole (MTZ).
b
Intermediate category is not shown, but can be derived by subtraction of %S and %R for each antimicrobial agent from %100.
c
Underlined values designate significant changes in %S and %R compared to Table 3 data as determined by chi-square test.
d
Clostridium spp. excludes Clostridium difficile.