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. Author manuscript; available in PMC: 2019 May 17.
Published in final edited form as: Bioconjug Chem. 2018 Mar 20;29(4):1364–1372. doi: 10.1021/acs.bioconjchem.8b00081

Table 1:

Degree of labeling of different antibodies following conjugation with PODS-FL

Antibody Type Constant region Ratio FL:Ab
Human plasma IgG Human Human IgG 2.1±0.1
Trastuzumab Humanized Human IgG1 2.0±0.1
huA33 Humanized Human IgG1 2.1±0.1
Cetuximab Chimeric Human IgG1 2.2±0.1

AR 9.6 Murine Murine IgG1 1.4±0.1
Mouse plasma IgG Murine Murine IgG 1.5±0.1