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. 2019 May 10;13:149. doi: 10.3389/fncel.2019.00149

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Copyright © 2019 Dietzmeyer, Förthmann, Leonhard, Helmecke, Brandenberger, Freier and Haastert-Talini.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Percentage of the individual paw usage abilities based on video-recorded reflex-based grasping test performed every 2 weeks over 16 weeks post-surgery. Pulling the bar with a force is the most complete ability to be recovered (Category 3). This recovery of gross motor function is achieved by all forelimbs of the ANG group (A). Among the artificial nerve guides corrCNG[F]s (D) led to the highest recovery rate. No statistical evaluation was applied. Values are given as percentages in relation to all evaluated forelimbs per group. (A) ANG, autologous nerve graft; (B) CNG, chitosan nerve guide; (C) CNG[F], chitosan-film enhanced chitosan nerve guide; (D) corrCNG[F], corrugated chitosan-film enhanced chitosan nerve guide: n = 8.