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Cytotoxic effect of the PTX (25 nM) and LAP (25 nM) combination on MCF-7 breast cancer cells. MCF-7 cells were treated with PTX-, LAP- and PTX/LAP-loaded micelles, and the mixture of free drugs for 24 h, 48 h or 72 h and then cell viability was determined by sulforhodamine B assay and expressed as a percentage of the control (mean ± SD, n =4). * p < 0.05 vs. control; PTX/LAP-loaded micelles vs. free PTX/LAP.
