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. 2019 Apr 16;8(4):101. doi: 10.3390/antiox8040101

Table 3.

Heavy metals/oligoelements of dental materials.

Heavy Metals from Dental Amalgams
Hg++ Median 25% 75% H
Control 1.6 1.25 2.3 H = 13.85, p < 0.001.
d0 1.9 1.9 3.7 * MW (* p < 0.005).
d90 1.15 0.34 2.1 *,# MW (# d90 vs. d0, p = 0.049); * p < 0.05 d90 vs. Cont
Ag Median 25% 75% H
Control 0.03 0.02 0.06 H = 9.3, p = 0.01.
d0 0.1 0.03 0.155 # MW (* p = 0.005 d0 vs. control). (# d90 vs. d0, p = 0.031)
d90 0.055 0.025 0.075
Sn Median 25% 75% H
Control 0.045 0.02 0.095 H = 6.27, p = 0.43.
d0 0.11 0.04 0.20 * MW (* d0 vs. Cont, p = 0.023).
d90 0.03 0.02 0.105 # MW (# d90 vs. d0, p = 0.047).
Zn++ Median 25% 75% H
Control 195 180 230 H = 5, p = 0.078
d0 245 208 275 * MW (* p < 0.05 d0 vs. control).
d90 210 180 242
Cu++ Median 25% 75% H
Control 13.5 10.5 35.5 H = 1.01, p = 0.6, n.s
d0 15 11 31
d90 13.5 10 19.5
Materials from Dental Titanium Alloys (Cr, Ni, Co)
Al Median 25% 75% H
Control 2.9 2.05 5.6 H = 4.6, p = 0.1, n.s.
d0 3 1.6 4.6
d90 1.6 1.5 2.4 * MW (* d90 vs. control, p = 0.029).
Cr Median 25% 75% H
Control 0.35 0.31 0.39 H=9.64, p = 0.008
d0 0.35 0.35 0.39
d90 0.41 0.36 0.45 *,# MW or Dunn’s.* p < 0.05 vs. cont, # p < 0.05 d90 vs. d0
Co Median 25% 75% H
Control 0.004 0.004 0.010 H = 4.97, p = 0.083, n.s.
d0 0.017 0.04 0.035 * MW * p < 0.05 d0 vs. control.
d90 0.06 0.035 0.012
Ni Median 25% 75% H
Control 0.055 0.04 0.10 H = 3.07, p = 0.21, n.s.
d0 0.09 0.08 0.16 * MW (* p < 0.05, d0 vs. Cont).
d90 0.11 0.04 0.16
V Media S.E.M F
Control 0.04 0.003 F (2.50) = 2.73, p = 0.07, n.s.
d0 0.031 0.004 * Bonferroni (p = 0.043, alpha (α) = 0.05, beta (β) = 0.42).
* p < 0.05 vs. control
d90 0.041 0.0035 # (# p < 0.05, d90 vs. d0)
* p < 0.05 vs. Cont # p < 0.05 d90 vs. d0 n.s: non significant effect (p > 0.05, n.s).

Percentiles analysis for heavy metals/oligoelement levels in Kruskal-Wallis (H) between patients with long-term titanium implant and dental fillings after 90 days of supplementation (d90, n = 16) as compared with their own basal levels (d0: before any supplementation, n = 16) and untreated (non-supplemented) controls without dental materials (control, n = 21). All heavy metals and oligoelements were expressed as μg/g of hair. H is the Krukal-Wallis analysis and F is ANOVA data. MW = Mann Whitney, S.E.M = standard error media; Control: controls without dental materials and non-supplemented (n = 21); d0: patients with long-term titanium implants and dental amalgam fillings restorations before any supplementation (d0, n = 16); d90: patients with long-term titanium implants and amalgams after 90 days of supplementation (n = 16); n.s: not significant effect, p > 0.05. * p < 0.05 vs. Control; # p < 0.05 d90 vs. d0.