Table 1.
Demographic and serum lipid summary by gender.
| Female (n = 921) | Male (n = 284) | ||||
|---|---|---|---|---|---|
| Age, Education | |||||
| Variable | Mean | SD | Mean | SD | p-Value |
| Age (range) | 83.8 (58.3–103.9) | 7.6 | 84.3 (64.2–101.0) | 7.1 | 3.8 × 10−1 |
| Education | 15.5 | 3.4 | 16.1 | 4.0 | 1.7 × 10−2 * |
| Serum Lipids | |||||
| Variable | Mean | SD | Mean | SD | p-Value |
| TG | 136.8 | 67.9 | 122.7 | 59.2 | 3.3e × 10−3 * |
| TC | 192.6 | 38.3 | 161.7 | 35.6 | 6.0 × 10−28 * |
| HDL-C | 63.9 | 18.4 | 52.5 | 15.2 | 4.9 × 10−18 * |
| LDL-C | 101.4 | 33.2 | 84.6 | 29.1 | 1.9 × 10−12 * |
| HDL-R | 0.338 | 0.092 | 0.331 | 0.088 | 3.5 × 10−1 |
| Serum Ethanolamine Glycerophospholipids | |||||
| Variable | Mean | SD | Mean | SD | p-Value |
| PE226 | 1.60 | 0.89 | 1.08 | 0.63 | 4.6 × 10−19 * |
| PL224 | 0.85 | 0.48 | 0.72 | 0.31 | 8.0 × 10−5 * |
| PL205 | 1.35 | 1.83 | 0.98 | 0.81 | 1.1 × 10−3 * |
| PL226 | 3.48 | 2.28 | 2.84 | 1.22 | 8.5 × 10−6 * |
| Plasmalogen Ratios | |||||
| Variable | Mean | SD | Mean | SD | p-Value |
| PL205/PE226 | 0.65 | 0.55 | 0.715 | 0.480 | 7.3 × 10−2 |
| PL226/PE226 | 1.81 | 0.88 | 2.18 | 1.00 | 1.6 × 10−9 * |
| PL205/PL224 | 1.94 | 2.49 | 1.67 | 1.98 | 1.0 × 10−1 |
| PL226/PL224 | 4.55 | 2.36 | 4.39 | 2.27 | 2.9 × 10−1 |
| PL205/PL226 | 0.36 | 0.23 | 0.337 | 0.186 | 1.4 × 10−1 |
| PBV | −0.09 | 0.21 | −0.075 | 0.179 | 2.9 × 10−1 |
Mean and standard deviation of the demographic variables, lipoproteins and phospholipid are given per gender. Serum lipid values are given in mg/dL. Internal standard–normalized values are given for ethanolamine glycerophospholipids and plasmalogen ratios. TG: Triglycerides, TC: Total cholesterol; HDL-C; HDL cholesterol; LDL-C: LDL cholesterol, HDL-R: HDL cholesterol to Total cholesterol ratio; PE226: Phosphatidyl ethanolamine 16:0/22:6; PL224: Plasmalogen ethanolamine 16:0/22:4; PL205: Plasmalogen ethanolamine 18:0/20:5; PL226: Plasmalogen ethanolamine 16:0/22:6; PL205/PE226: ratio of Plasmalogen ethanolamine 18:0/20:5 to Phosphatidyl ethanolamine 16:0/22:6; PL226/PE226: ratio of Plasmalogen ethanolamine 16:0/22:6 to Phosphatidyl ethanolamine 16:0/22:6; PL205/PL224: ratio of Plasmalogen ethanolamine 18:0/20:5 to Plasmalogen ethanolamine 16:0/22:4; PL226/PL224: ratio of Plasmalogen ethanolamine 16:0/22:6 to Plasmalogen ethanolamine 16:0/22:4; PL205/PL226: ratio of Plasmalogen ethanolamine 18:0/20:5 to Plasmalogen ethanolamine 16:0/22:6; PBV: Averaged value of the five mean normalized (gender-based) log10 transformed plasmalogen ratios. For clarity, significant p values (p < 0.05) are indicated by an asterisk *.