Skip to main content
. 2019 May 10;10:512. doi: 10.3389/fphar.2019.00512

FIGURE 1.

FIGURE 1

Orally active EET analog, EET-A, decreased renal cortical mRNA expression of CXC chemokine receptor CXCR3 (A) and its ligands CXCL 9 (B), CXCL10 (C) in a mouse model of systemic lupus erythematosus (SLE). EET-A also reduced mRNA expression of CXC chemokine receptor CXCR4 (D) and CXC chemokines CXCL13 (E) and CXCL16 (F) in the kidney cortex of SLE mice. All data are expressed as Mean ± SEM, P < 0.05 vs. Non SLE-Vehicle, #P < 0.05 vs. SLE-Vehicle, n = 10–12/group. NZBWF1 (SLE) and NZW/LacJ (Non SLE).