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. 2019 Mar 29;10(4):225. doi: 10.3390/mi10040225

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(a) Composition of the cell capture array: disulfide-biotin has been doped into the vertical PPy nanowires during electrochemical polymerization and linked to the biotin-linked anti-EpCAM antibodies through addition of streptavidin. (b) Captured cells can be released either by applying a voltage swelling the PPy or the addition of glutathione for cleavage of the disulfide bond. (c) Electrochemical detection after labeling of captured cells with HRP-nanoparticle-linked antibodies. Reprinted from [45], Copyright 2014, with permission from Elsevier.