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IL1B controls expression of many shared mid-level regulators in the zebrafish (top), medaka (bottom), and mouse (middle) liver datasets, including the key immune and inflammation APR regulator TNF. Genes in red and green are modulated DEGs, and genes in orange and blue are predicted by IPA to be up and down, respectively. Due to the robust dataset in medaka, the number of genes up and down-modulated are listed in red and green, respectively.
