Table 4.
Single nucleotide polymorphisms (SNPs) examined for interactions with education level impacting median premedication systolic and diastolic blood pressure.
| SNP in education interaction term | p-value for the interaction between high school and SNP | p-value for interaction between college and SNP |
|---|---|---|
| Systolic Blood Pressure | ||
| rs4593967_A | 0.886 | 0.858 |
| rs10921895_G | 0.896 | 0.746 |
| rs3804485_C | 0.260 | 0.863 |
| rs11066700_A | 0.178 | 0.200 |
| Diastolic Blood Pressure | ||
| rs950928_G | 0.175 | 0.298 |
| rs8056711_C | 0.175 | 0.297 |
| rs9931167_A | 0.927 | 0.503 |
| rs11648873_T | 0.940 | 0.478 |
| rs28681321_A | 0.941 | 0.461 |
| rs6687976_A | 0.052 | 0.996 |
| chr16.19642355_G | 0.094 | 0.110 |
| rs3095994_A | 0.738 | 0.726 |
| rs1273518_G | 0.218 | 0.648 |
| rs1858975_A | 0.076 | 0.091 |
| rs4593967_A | 0.512 | 0.768 |
| rs8046628_C | 0.181 | 0.316 |
| rs6497402_A | 0.062 | 0.085 |
| chr16.19641087_A | 0.064 | 0.076 |
Median premedication systolic blood pressure (SBP) and diastolic blood pressure (DBP) were outcomes in the linear regression models. Covariates included in the models were age, age squared, sex, body mass index, smoking status, and African ancestry. The main effect of education and the SNP, as well as the SNP × education interaction term were also included in the model. Less than high school was the reference group within the regression models. The p-value for the potential SNP-education interaction is bolded.