Table 1.
Model base-case parameters.
| Parameter | Base case | Variance | Reference |
|---|---|---|---|
| PATIENT COHORT | |||
| Age, years | 73 | 2.3 | (20) |
| Gender, % female | 29.8 | 0.18 | (20) |
| Obese, % | 35 | 0.48 | (18) |
| Morbid obesity, % | 6 | 0.24 | (18) |
| Diabetes, % | 45.2 | 0.19 | (20) |
| CLINICAL SETTINGS | |||
| Time on MV, days | 0.5 | 0.0001 | (19) |
| ICU time, days | 1 | 0.0001 | (19) |
| Hospital time, days | 8 | 1.79 | (20) |
| Prolonged MV patients | 10.6 | 0.0001 | (18) |
| ECG monitoring, days | 8 | 1.79 | (20) |
| Home discharge | 74.5 | 0.17 | (20) |
| In-hospital mortality, % | 2.7 (after 13 days) | 0.067 | (20) |
| DSWI, % of SSIs | 40.75 | 2.6 | (4) |
| SSI additional length of stay, days | 13.3 | 20.8 | (21) |
| DSWI additional length of stay, days | 24 | 5 | (22) |
| False alarms, N per 100 patient days | 97.9 | 1.43 | (16) |
| Leads-off alarms, N per 100 patient days | 40.9 | 4.92 | (16) |
| RELATIVE RISK OF EVENTS | |||
| spECG false alarms, RR | 0.81 | 0.13 | (16) |
| spECG leads-off alarms, RR | 0.71 | 0.15 | (16) |
| DSWI RR, BMI morbidly obese | 6.45 | 0.40 | (18) |
| Hospital mortality RR, morbidly obese | 1.64 | 0.18 | (18) |
| Diabetes RR, DSWI | 1.71 | 0.20 | (19) |
| COSTS | |||
| rECG cost per patient use | 9.08 | 1.66 | † |
| spECG purchase cost | 15 | 2 | ‡ |
| CABG | 10,244 | 2,664 | (10) |
| Mechanical ventilation | 756 | 210–906 | (23) |
| ICU per day | 2,536 | 2,197–3,066 | (23) |
| Nurse time, $ per hour | 58 | 4.6 | (24) |
| Inpatient SSI* | −158 | 210 | (5) |
| Outpatient care for SSI | 2,583 | 838 | (25) |
| Readmission for DSWI | 23,586 | 6,815 | (9) |
| Future care costs | 4673.1 | 524 | (10) |
| Decrement, future care costs | 92.29 | 215 | (10) |
| QUALITY OF LIFE | |||
| Baseline | 0.85 | 0.158 | (10) |
| CABG | 0.741 | 0.191 | (10) |
| Mechanical ventilation | −0.39 | −0.59–0.09 | (26) |
| ICU stay | 0.402 | 0.36–0.44 | (27) |
| General ward stay | 0.52 | 0.45–0.59 | (28) |
| SSI | 0.198 | 0.04–0.8 | (11, 29) |
Costs are in 2016 USD, with conversion from the published figure using the CPI for medical care (Series Id: CUUR0000SAM).
Surgical site infection is generally found to increase hospital length of stay and hospital costs, but reduce the mean cost per day in hospital.
†Calculated value ‡Data on file with Cardinal Health.