Figure 3.

Segregated connectivity of the cortico-striatal pathway. The cortico-striatal neurons in the deeper (red) and upper (green) parts of cortical layer 5 (L5) project preferentially to the striosome (red) and matrix (green) compartments, respectively. The gradient of colors indicates polarized distribution of cortico-striatal connectivity. The light red and light green indicate parts of the striatum that receive inputs predominantly from the limbic cortex. The dark red and dark green indicate parts of the striatum that receive inputs predominantly from the sensori-motor cortex. Abbreviations: CN, caudate nucleus; NA, nucleus accumbens; Put, putamen. Orientations: the lateral (L) is to the right, the dorsal (D) is to the top.