Table 1.
Study Participant | Drug | Delusions | Conceptual Disorganization | Hallucinatory Behavior | Excitement | Grandiosity | Suspiciousness/Persecution | Hostility |
---|---|---|---|---|---|---|---|---|
male 1 | Δ9-THC | ✕ | ✓ mild | ✕ | ✓ minimal | ✕ | ✓ mild | ✕ |
male 2 | Δ9-THC | ✕ | ✓ mild | ✕ | ✓ mild | ✓ minimal | ✕ | ✕ |
male 3 | Δ9-THC | ✕ | ✓ severe | ✓ mild | ✓ moderate | ✓ moderate | ✓ mild | ✕ |
male 4 | Δ9-THC | ✕ | ✓ minimal | ✕ | ✓ minimal | ✕ | ✕ | ✕ |
male 5 | Δ9-THC | ✕ | ✓ moderate | ✓ mild | ✕ | ✕ | ✓ minimal | ✕ |
male 6 | Δ9-THC | ✓ mild | ✓ moderate | ✓ mild | ✓ moderate | ✓ moderate | ✕ | ✕ |
male 7 | Δ9-THC | ✕ | ✓ moderate | ✓ mild | ✓ mild | ✕ | ✓ minimal | ✕ |
female 1 | Δ9-THC | ✕ | ✓ mild | ✕ | ✕ | ✕ | ✕ | ✓ mild |
female 2 | Δ9-THC | ✕ | ✓ mild | ✓ mild | ✕ | ✕ | ✕ | ✕ |
female 3 | Δ9-THC | ✕ | ✓ mild | ✕ | ✓ mild | ✕ | ✕ | ✕ |
female 4 | Δ9-THC | ✕ | ✓ moderate | ✓ minimal | ✓ mild | ✕ | ✓ mild | ✓ mild |
female 5 | Δ9-THC | ✕ | ✓ mild | ✓ mild | ✓ mild | ✕ | ✓ mild | ✕ |
female 6 | Δ9-THC | ✕ | ✓ moderate | ✓ mild | ✓ minimal | ✕ | ✕ | ✕ |
female 7 | Δ9-THC | ✕ | ✓ moderate | ✕ | ✕ | ✕ | ✓ minimal | ✕ |
female 8 | Δ9-THC | ✓ moderate | ✓ moderate/severe | ✓ severe | ✕ | ✓ moderate | ✓ minimal | ✕ |
female 9 | Δ9-THC | ✓ minimal | ✓ moderate | ✓ moderate | ✕ | ✕ | ✓ moderate | ✓ mild |
male 1 | placebo | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ |
male 2 | placebo | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ |
male 3 | placebo | ✕ | ✕ | ✕ | ✓ minimal | ✕ | ✕ | ✕ |
male 4 | placebo | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ |
male 5 | placebo | ✕ | ✓ mild | ✕ | ✕ | ✕ | ✕ | ✕ |
male 6 | placebo | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ |
male 7 | placebo | ✕ | ✓ mild | ✓ minimal | ✕ | ✕ | ✕ | ✕ |
female 1 | placebo | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ |
female 2 | placebo | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ |
female 3 | placebo | ✕ | ✕ | ✕ | ✓ minimal | ✕ | ✕ | ✕ |
female 4 | placebo | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ |
female 5 | placebo | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ |
female 6 | placebo | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ |
female 7 | placebo | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ |
female 8 | placebo | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ |
female 9 | placebo | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ | ✕ |
Δ9-THC, (−)-trans-Δ9-tetrahydrocannabinol; symptoms highlighted in bold were still observable 2.5 h after the injection.