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. 2019 Apr 25;9(4):93. doi: 10.3390/brainsci9040093

Table 4.

Subjects’ quotes.

Study Participant Δ9-THC Symptom
male 1 ‘I was so stressed, irritable, and prone to anger that I started an argument with my partner the afternoon after the study’ Hostility, irritability, mood lability
male 2 ‘I feel I am all over the place and can’t stop laughing, thinking you will expose me, I will say something stupid or strange’ Conceptual disorganization, thought disorder, loosening of associations, excitement
male 3 ‘I can’t follow my thoughts, I am not able to think’ Conceptual disorganization, racing thoughts
male 3 ‘I can understand things better and look for details, I am superior to others’ Grandiosity
male 3 ‘I might have done something wrong, not willing to say’ Feelings of guilt
male 3 ‘I am thinking about death and cemeteries’ Unusual thought content
male 6 ‘The injection changed me into someone with increased abilities’ Grandiosity
male 7 ‘I am feeling quite confused and disoriented, like time is passing slower and the space is different, like from a camera zoom’ Conceptual disorganization, disorientation
female 1 ‘I am not interested and I am not willing to talk, I don’t care, I want just to go... I feel down, under the weather; maybe I am depressed’ Negative symptoms, depression
female 4 ‘What have you done to me? I understand, you want to make me paranoid with brainwashing questions...’ Suspiciousness/paranoia with loss of insight
female 4 ‘What an apple and a ball have in common...You can eat the apple, but not the ball’ Difficulty in abstract thinking
female 5 ‘I thought you were going to attack me, people are entering the room to check on me’ Suspiciousness/paranoia, ideas of reference
female 7 ‘What an apple and a ball have in common...You can put the apple in the ball’ Difficulty in abstract thinking
female 8 ‘My mind went blank, empty, with no thoughts’ Thought blocking
female 8 ‘The ventilator’s noise is louder...This noise is actually rain, it’s raining inside the room, I can see and feel it, there is a black sky with seven blue drops, I can count them, someone has opened the ceiling to let the rain in, and put my bed closer to the ceiling...Maybe someone is projecting a sky in front of me’ Inability to ‘filter’ out irrelevant background stimuli, hallucinatory behavior, secondary delusions
female 9 ‘Is this real? Is this a fake interview made by a fake doctor, like a Truman show?’ Depersonalization/derealization
female 9 ‘Colors are brighter, noises louder, and I have something making a noise in the back of my head’ Hallucinatory behavior
male 3, 7; female 5, 7 ‘I think I am going to chock up...something is wrong with my body...the heart is racing’ Preoccupation/somatic concern, anxiety/tension
Study Participant Placebo Symptom
male 7 ‘I felt spaced out, a little bit paranoid and upset after a conversation with someone who had a strange facial expression’ Suspiciousness/paranoia

Δ9-THC, (−)-trans-Δ9-tetrahydrocannabinol.