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. 2019 Apr 25;9(4):93. doi: 10.3390/brainsci9040093

Table 5.

Additional symptoms.

Study Participant Δ9-THC
physical reactions
female 2 generalized tremors, vagal reaction
female 3 about to faint
female 5 about to faint, paleness
female 6 about to faint, orthostatic hypotension, sick feeling
female 8 flushing
observed symptoms
males 2, 3, 6; females 1, 2, 3, 4, 8 Different handwriting, errors and corrections in filling out the questionnaires (still present at 2.5 h after the injection for males 3 and 6)
male 6 The participant kept the arm in a distinctively awkward position for 30 min
female 4 The participant committed errors when asked four times to recall words related to a memory task (night instead of black 2/4, vegetable instead of apple 3/4, crisis instead of cries 4/4)
female 8 The participant was internally absorbed and didn’t engage at all with a cognitive task
reported long-lasting symptoms (telephone follow-up)
male 1 suspiciousness, hostility, tension, and poor impulse control until afternoon
male 1 headache, sick and weak feeling, fatigue, exhaustion, physical and mental strain until day after
male 2 tiredness, sleepiness, postprandial somnolence
male 6 disorientation and tiredness until evening
female 5 tiredness and cravings for savory foods until afternoon
female 6 tiredness, sleepiness, and hunger until the end of the day
female 9 sleepiness, thirst, and hungry
females 1 and 4 Symptoms reported during the trial were the same experienced in the past when using recreational cannabis
Study participant Placebo
physical reactions
female 1 flushing, drowsiness, stomach pain
female 6 flushing, increase in heart rate, heavy chest feeling
reported long-lasting symptoms (telephone follow-up)
male 7 suspiciousness until afternoon

Δ9-THC, (−)-trans-Δ9-tetrahydrocannabinol.