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. 2019 Apr 4;11(4):167. doi: 10.3390/pharmaceutics11040167

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Photomicrographs of untreated and exposed to HQ formulations mouse skin. (A) Untreated skin (20× magnification); (B) Skin exposed to HQ1 formulation (20× magnification); (C) Skin exposed to HQ1 formulation (40× magnification); (D) Skin exposed to HQ2 formulation (20× magnification); (E) Skin exposed to HQ3 formulation (20× magnification); (F) Skin exposed to HQ4 formulation (20× magnification). Key: 1- Stratum corneum, 2- Hair follicle, 3- Sebaceous gland, 4- Possible inflammatory cell, 5- Possible epithelial necrosis, 6- Possible drug depot accumulation.