Figure 10.

Effect of NGF and NGF(1-14) peptides on protein tyrosine phosphatase activity. Representative western blotting (A,B) and densitometric analyses (C) of total tyrosine phosphorylation in PC12 cells treated for 15 min with 50 μM NGF(1-14) peptides or NGF protein in the absence (☐) or in the presence of 1 μM CuSO₄ (■) or 50 μM BCS 24 h pre-treated medium (■). Data obtained from at least three independent experiments. (*** p < 0.001 versus control; §§§ p < 0.001 versus CuSO₄; ### p < 0.001 versus BCS; one-way Anova).