Skip to main content
. 2019 Mar 29;9(4):126. doi: 10.3390/biom9040126

Figure 3.

Figure 3

z-VAD-FMK reversed greensporone A-induced cell cycle and caspase activation in leukemic cells. Leukemic cells K562 and U937 cells were treated with greensporone A and z-VAD-FMK alone and in combination for 24 h. (A,B) z-VAD-FMK reversed greensporone A-induced increased SubG0 phase and apoptosis, respectively. (C–E) Caspase activation induced by greensporone A in K562 and U937 leukemic cells were reversed by z-VAD-FMK as analyzed by western blot and flow cytometry. The graph displays the mean ± SD of three independent experiments. * P < 0.05, ** P < 0.01, *** P < 0.001.