Table 1.
Average particle size (nm), polydispersibility index and zeta potential (mv) of liposomes prepared by thin film hydration homogenization, thin film hydration ultrasonication and Mozafari method expressed as mean ± standard deviation where * represents statistical significant (*p < 0.05) in average particle size of Mozafari method in comparison with homogenization and ultrasonication method.
Formulation Techniques | Average Particle Size (nm) | Polydispersibility Index (PDI) | Zeta Potential (mV) |
---|---|---|---|
Thin film hydration Homogenization | 186.3 ± 4.4 | 0.370 ± 0.001 | −13.0 ± 5.0 |
Thin film hydration ultra-sonication | 196.2 ± 16.1 | 0.294 ± 0.084 | −14.0 ± 3.4 |
Mozafari method | 260.0 ± 23.0* | 0.348 ± 0.087 | −9.8 ± 0.3 |