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. 2019 Apr 14;8(4):353. doi: 10.3390/cells8040353

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Association of f508del-CFTR with chaperones compared to DD/AA-CFTR. The protein affinity for the two variants under analysis was assessed by calculating log₂(Condition 1) − log₂(Condition 2)| and shown for variants with −log₁₀(p-value) ≥ 1.6 (corresponding to p < 0.025) as in Figure 4 (see Materials and Methods).